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Dermatologist-Approved Dermatologist-Approved
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Dermatologist-Approved Dermatologist-Approved

Trusted By 50,000+ Customers & Physicians

STOP CHASING SYMPTOMS.
TREAT THE ROOT CAUSE OF
SUN DAMAGED SKIN
Powered by Nobel Prize-winning technology and infused with DNA repair enzymes–our formulas treat symptoms at their root cause before they reach the surface of the skin as wrinkles, age spots, or uneven tone and texture.
START YOUR REPAIR JOURNEY
60-Day Money Back Guarantee
MADE IN THE USA
DERMATOLOGIST RECOMMENDED
CLINICAL RESULTS
DNA REPAIR ENZYMES
FDA APPROVED MANUFACTURING
MADE IN
THE USA
DERMATOLOGIST
RECOMMENDED
CLINICAL
RESULTS
DNA REPAIR
ENZYMES
FDA APPROVED
MANUFACTURING
MADE IN
THE USA
DERMATOLOGIST
RECOMMENDED
CLINICAL
RESULTS
DNA REPAIR
ENZYMES
FDA APPROVED
MANUFACTURING
Clinically Formulated Solutions
Targeted DNA repair for daily care and long-term prevention and protection.
Best Sellers
Targeted Treatments
New
All
The Science Behind DNA Repair
Why sunscreen and traditional skincare are not enough.
Daily UV Exposure Causes DNA Damage
Ultraviolet radiation creates DNA lesions in skin cells every day—even when sunscreen is applied.
Natural Repair Declines With Age
As skin ages, its ability to repair DNA damage slows, allowing mutations to accumulate and accelerate visible aging.
Photozyme Supports the Repair Process
Photozyme replenishes essential DNA repair enzymes to help skin correct damage at the source and restore cellular function.
VISIBLE REPAIR. PROVEN RESULTS.
Actual patient results. Images taken by Vivian Bucay, MD, FAAD San Antonio, Texas using the VISIA Complexion Analysis System
Trusted by Dermatologists
Formulated for clinical results and long-term skin health.
“Supporting DNA repair is essential for maintaining healthy skin over time. Photozyme is well tolerated, non-irritating, and appropriate for daily use even in sensitive or post-procedure patients.”
Reeli Reinu, PA-C (Dermatology)
Our Story
About Photozyme MD
Photozyme MD was built around one idea: most skincare protects the surface, but aging starts deeper. With decades of experience in dermatology, our founders focused on what actually drives visible aging: DNA damage caused by daily sun exposure. That’s why every Photozyme formula is designed to do more than hydrate or temporarily smooth the skin. We use DNA repair enzymes to support your skin’s natural ability to repair damage before it shows up as wrinkles, sun spots, and uneven skin tone & texture.


Originally developed for use in dermatology practices, Photozyme products have been trusted by professionals to support skin recovery, daily repair, and long-term skin health. Today, we continue to combine clinically proven technology, dermatologist expertise, and high-quality manufacturing standards to create formulas that actually target the root cause of aging.
Learn About US
Results Rooted In Skin Science
Meaningful improvements driven by cellular repair.
  • Supports repair of UV-induced sun damage
  • Helps improve skin tone, texture, and resilience
  • Reduces visible signs of photoaging
  • Strengthens the skin’s natural barrier
  • Non-irritating and suitable for sensitive skin
  • Designed for consistent, long-term use
START YOUR REPAIR JOURNEY
60-Day Money Back Guarantee
RECOMMENDED BY DERMATOLOGISTS
See why 50,000+ customers & physicians choose Photozyme
stars
DNA Youth Recovery Serum
“This serum feels beautiful on the skin and works great with my other products with no pilling or irritation. It's soothing and not greasy at all. It has helped to fade my hyperpigmentation and overall appearance of my skin. I use daily and before my red light therapy. Highly recommend.”
TO
stars
So far so good
“I really like the way this feels on my skin. As for repair, it’s only been 3 weeks so I haven’t noticed much difference but I will continue to use and have bought a second bottle. This was highly recommended by Dr Ellen Gendler on IG and I trust her recommendations as she is very knowledgeable.”
CB
stars
Love it!
“Lightweight serum, it hydrates, and I trust the brand that enzymes are repairing and protecting the skin. My skin was in good condition before I started to use this serum, so I don't see much difference, but I will keep using it.”
T
stars
BEST RETINOL
I can’t believe how effective and yet non-irritating this retinol formula is. I don’t have to sandwich it in like I usually had to. Great, great retinol!
JH
stars
Cand E Ferulic serum
I’ve tried tons of VitaminC serums. This is by far the best I’ve EVER!
HG
stars
Economical
Bottle lasted a long time. Little goes a long way.
KA
stars
Vitamin C
Best vitamin c and then some!
JH
Try It Risk-Free for 60 Days
We are so confident in our DNA repair enzymes that we take all the risk. Try it, use it, and if you don't feel the difference in your skin's health, simply email us for a prompt, courteous refund. No questions asked.
Try Risk Free Today
60-Day Money Back Guarantee
Your Questions, Answered
Can I use Photozyme with my current skincare routine?

Yes. Photozyme is designed to fit easily into most skincare routines. It works well alongside common products like moisturizers, vitamin C, sunscreen, and gentle exfoliants. Many users apply Photozyme first, then follow with their regular moisturizer and SPF.

Why is targeting the “root cause” of skin aging important?

Most skincare products focus on surface-level symptoms like dryness or fine lines. Photozyme is designed to go deeper by supporting the repair of UV-damaged skin cells, the root cause behind visible aging. By addressing this damage early, it helps reduce the appearance of wrinkles, sun spots, and uneven skin over time.

Is Photozyme safe for sensitive skin?

Photozyme is formulated to be gentle enough for daily use and is commonly used by people with sensitive or aging skin. However, as with any skincare product, we recommend doing a small patch test before applying it to your full face.

Can I use Photozyme after cosmetic or dermatological procedures?

Yes. Photozyme was originally developed for physician offices and has been used by dermatologists to support skin recovery after treatments such as laser procedures, peels, and other in-office treatments. Always follow your dermatologist’s guidance after procedures.

Do I need to stop using my current anti-aging products?

Not necessarily. Photozyme is often used alongside other skincare products. Many users keep their existing routine and add Photozyme as a targeted serum to support skin repair and overall skin health.

How often can I use DNA repair enzymes?

You can use DNA repair enzymes as often as you want. We recommend using it at a minimum in the morning and night.

Will Photozyme make my skin more sensitive to the sun?

No. Photozyme does not contain ingredients that increase sun sensitivity. However, sunscreen is always recommended during the day to help protect your skin and maintain results.

How much serum should I apply?

A small amount goes a long way. Typically, 1–2 pumps is enough to cover the face and neck. Gently massage it into clean skin and allow it to absorb before applying other products.

Is Photozyme suitable for all skin types?

Photozyme is suitable for most skin types including normal, dry, combination, and mature skin. If you have a specific skin condition, we recommend consulting your dermatologist before starting any new skincare product.

Can men use Photozyme?

Absolutely. While many of our customers are women, Photozyme is effective for anyone looking to support healthier-looking skin and reduce visible signs of sun damage.

How does Photozyme work?

Photozyme combines 3 essential DNA repair enzymes with hydration and antioxidant support to target the root cause of aging skin. 

1. DNA Repair Enzymes

These specialized enzymes locate damaged skin cells caused by UV exposure and support the skin’s natural ability to repair them before they appear as wrinkles or discoloration.

2. Collagen Protection

Photozyme’s clinically studied technology helps slow collagen degradation in the lower layers of the skin, helping maintain smoother, firmer skin over time.

3. Hyaluronic Acid Hydration

Hyaluronic acid attracts and holds moisture in the skin, helping improve softness, elasticity, and overall skin comfort.

4. Antioxidant Defense

Antioxidants neutralize free radicals created by UV exposure and environmental stress, helping protect the skin from future damage.

What can Photozyme help with?

Photozyme is designed to address some of the most common signs of skin aging caused by sun exposure and environmental damage.

It helps with:

• Fine lines and wrinkles
• Uneven skin tone and sun spots
• Rough or dull skin texture
• Visible signs of sun damage
• Dry or dehydrated skin
• Loss of smoothness and radiance
• Skin recovering after dermatological treatments

How fast will I see results?

Most women report more hydrated and smoother skin after the first week of use. 

After 3–4 weeks of consistent use, many begin to notice:

• Skin looks smoother and more even, with less visible roughness

Sun spots and discoloration appear lighter, creating a more uniform tone

Fine lines look softer, especially around the eyes and mouth

Because the skin renews itself in natural cycles, the most noticeable improvements typically appear after 6–8 weeks, when newly repaired skin cells reach the surface.

With continued daily use, Photozyme helps support healthier skin over time.

Trusted by 50,000+ Customers & Physicians

Stop Managing Damage. Start Repairing It.
Join thousands using DNA repair enzymes to protect their skin & repair sun damage.
START YOUR REPAIR JOURNEY
60-Day Money Back Guarantee
Elevate Your Skincare Journey, Join Our Loyalty Program
Earn points every time you shop, plus enjoy exclusive benefits and offers!
  • Earn 1 point with every $1 spent
  • 200 points for every friend you refer
  • Free bonus points on your birthday
  • Exclusive early access to new products, promotions, and more
CLINICAL INSIGHTS ON SKIN HEALTH
Thoughtful articles exploring skin biology, clinical care, and modern dermatology.
May 22, 2026
Photozyme explains how to get rid of age spots with topical treatments, DNA repair technology, professional procedure...
May 21, 2026
Photozyme covers uneven skin tone causes, treatments, and the lifestyle factors that determine how quickly your skin ...
April 20, 2026
Learn whether DNA repair enzymes do or don’t help with fine lines. Examine the ingredients for balanced-looking skin ...
April 19, 2026
Learn what the benefits are of using DNA repair enzymes after a chemical peel. Photozyme explains how they support re...
April 18, 2026
Learn whether DNA repair enzymes improve skin texture. See how Photozyme supports smoother-looking skin through repai...
April 17, 2026
Find the best time to use DNA repair enzyme products with Photozyme. Learn how timing supports skin repair and daily ...
Free Shipping on US Orders $50+ Free Shipping on US Orders $50+
60-Day Money-Back Guarantee 60-Day Money-Back Guarantee
Dermatologist-Approved Dermatologist-Approved
Free Shipping on US Orders $50+ Free Shipping on US Orders $50+
60-Day Money-Back Guarantee 60-Day Money-Back Guarantee
Dermatologist-Approved Dermatologist-Approved