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Free Shipping on US Orders $50+
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Dermatologist-Approved
Free Shipping on US Orders $50+
60-Day Money-Back Guarantee
Dermatologist-Approved
Free Shipping on US Orders $50+
60-Day Money-Back Guarantee
Dermatologist-Approved
Free Shipping on US Orders $50+
60-Day Money-Back Guarantee
Dermatologist-Approved
Trusted by 50,000+ Customers & Physicians
Repair Sun Damage at the
Cellular Level
3 DNA repair enzymes target aging at the source reducing spots, lines, and uneven skin.
START YOUR REPAIR JOURNEY ➝
60-Day Money Back Guarantee
Cellular-level DNA repair
Reduces fine lines, wrinkles & UV spots
Deep hydration & plumping
What People Are Saying About Photozyme
IF YOU’RE DEALING WITH ANY OF THESE
problems THIS IS FOR YOU
Photozyme is built for skin showing signs of accumulated damage especially from UV exposure and aging.
Sun Spots & UV
Damage
Fine Lines & Early
Wrinkles
Uneven Skin
Tone
Loss of Firmness &
Elasticity
Dull, Tired-Looking
Skin
Dehydrated, Rough
Texture
START YOUR REPAIR JOURNEY ➝
Sunscreen blocks damage.
DNA Repair enzymes reverse it.
Sunscreen helps prevent new UV damage, but it can't undo the DNA damage that's already there. In peer-reviewed studies, topical DNA repair enzymes measurably reduced the molecular markers of sun damage in skin.
61%
Reduction in CPDs
Sunscreen + DNA repair enzymes vs. 35% for
sunscreen alone, over 6 months
53%
Fewer UV-damage markers
Drop in cyclobutane pyrimidine dimers after 8 weeks of topical use
18 / 19
Participants improved
Showed a significant decrease in CPD and p53 damage markers
What the studies found
DNA repair enzymes outperformed sunscreen alone at reducing sun damage.
In a 6-month randomized trial of patients with sun-damaged skin, adding DNA repair enzymes to SPF 50 cut UV-damage markers (CPDs) by 61% — versus 35% for sunscreen alone — and reduced areas of pre-cancerous change significantly more.
Carducci et al. · J Drugs Dermatol, 2015 · Randomized clinical study (n=28)
Photolyase prevented ~93% of new UV damage when paired with sunscreen.
With repeated sun-simulated exposure, sunscreen plus photolyase prevented about 93% of CPD formation (versus 62% for sunscreen alone) and reduced UV-triggered cell death by roughly 82%.
Carducci et al. · Mol Med Rep, 2012 · Controlled exposure study (n=10)
8 weeks of topical use reversed damage at the molecular level.
A DNA recovery serum with three DNA repair enzymes lowered cyclobutane pyrimidine dimers by ~53% and mutant p53 by ~37% in sun-damaged skin. 18 of 19 participants showed a significant improvement.
Carducci et al. · J Drugs Dermatol, 2013 · 8-week clinical study (n=19)
Repair is the layer sunscreen can't provide.
Dermatology's Skin Health & Beauty Pyramid places protection and repair at the foundation of skin care: sunscreens and antioxidants limit damage, while DNA repair enzymes work on damage that has already occurred.
Carducci et al. · J Drugs Dermatol, 2014 · Clinical framework
Results are drawn from published clinical and experimental studies of topical DNA repair enzymes (photolyase, endonuclease, and OGG1). Individual results
vary. Some studies were industry-supported or used small samples; figures reflect the outcomes reported in each cited paper.
START YOUR REPAIR JOURNEY ➝
90-Day Real User Results
These before-and-after images document a 90-day trial using Photozyme daily. The user evaluated the serum over three months to see whether DNA repair enzymes in skincare could visibly improve sun damage, skin tone, and signs of aging.
TARGETED DNA REPAIR FOR AGING SKIN
Your skin faces daily UV damage that builds up beneath the surface even with sunscreen. Over time, this leads to fine lines, uneven tone, and visible signs of aging.
This serum is designed to target that damage at its source, helping repair and restore skin for a smoother, more even, and healthier-looking appearance.
Made in
the USA
dermatologist
recommended
clinical
results
dna repair
enzymes
fda approved
manufacturing
Made in
the USA
dermatologist
recommended
clinical
results
dna repair
enzymes
fda approved
manufacturing
Made in
the USA
dermatologist
recommended
clinical
results
dna repair
enzymes
fda approved
manufacturing
WHY YOUR SKIN NEEDS THIS
Every day, UV exposure damages your skin’s DNA, even when you’re wearing sunscreen. Over time, your body produces fewer DNA repair enzymes, allowing this damage to build up beneath the surface. That’s when fine lines, uneven tone, and sun spots start to appear.
By supporting your skin’s natural ability to fix damage at the cellular level, this serum helps prevent visible aging before it fully surfaces, not just treat it after.
SHOP ÈLEVÈ NECK & DÉCOLLETÉ ➝
Comprehensive Benefits for
Skin Renewal and Firmness
DNA Repair & Cellular Renewal
Helps repair cellular damage caused by environmental, promoting healthier, more resilient skin.
Softens Fine Lines & Wrinkles
Helps with smoothing out lines and early wrinkles for a more youthful, refreshed appearance over time.
Deep Hydration & Moisture Retention
Hyaluronic acid and glycerin help lock in moisture, improving skin smoothness and reducing the appearance of fine lines.
Antioxidant Protection & Defense
Helps neutralize harmful particles caused by everyday pollution and sun exposure to protect and maintain healthier-looking skin over time.
START YOUR REPAIR JOURNEY ➝
START YOUR REPAIR JOURNEY ➝
How to use
Lightweight, fast-absorbing, and suitable for morning and night use.
1. Apply
After cleansing, apply 1–2 pumps to face. For best results use morning and night.
1. Apply
After cleansing, apply 1–2 pumps to face. For best results use morning and night.
2. Absorb
Gently smooth until fully absorbed. The lightweight formula sinks in fast.
2. Absorb
Gently smooth until fully absorbed. The lightweight formula sinks in fast.
3. Results
Skin looks smoother, firmer, and visibly more radiant with continued use.
3. Results
Skin looks smoother, firmer, and visibly more radiant with continued use.
Formulated with Advanced Actives
Formulated with
Advanced Actives
A powerful blend of clinically backed ingredients that work together to strengthen, hydrate, and repair your skin.
DNA Repair Enzymes
Helps support the skin’s natural ability to identify and repair UV-induced damage at the cellular level.
Hyaluronic Acid
Deeply hydrates the skin by attracting and retaining moisture for a plumper, smoother look.
Ergothioneine
A powerful antioxidant that helps defend skin against environmental stress and free radical damage.
Plant Extracts
Helps support skin renewal and resilience, promoting a healthier-looking complexion over time.
START YOUR REPAIR JOURNEY ➝
Hear from Our Happy Customers
See why 50,000+ customers & physicians choose Photozyme
Try It Risk-Free for 60 Days
Try it, use it, and if you don't feel the difference in your skin's health,
simply email us for a prompt, courteous refund. No questions asked.
START YOUR REPAIR JOURNEY ➝
Frequently Asked Questions
How is this different from a regular serum?
Most serums focus on surface hydration or temporary smoothing. This formula is designed to support skin at a deeper level by targeting visible effects of accumulated UV damage.
What exactly does “DNA repair” mean in skincare?
It refers to supporting the skin’s natural processes that help address visible effects of UV-induced damage at a cellular level. This does not replace sunscreen—it works alongside it to improve overall skin health and appearance.
Do I still need sunscreen if I use this serum?
Yes. This serum does not protect against UV rays. Sunscreen is still essential in the morning. Think of sunscreen as prevention and this serum as repair support for past and ongoing damage.
Will this help with sun spots and pigmentation?
Yes, with consistent use. The formula is designed to help reduce the appearance of UV spots over time by supporting skin renewal and improving overall tone.
When should I use it?
Use it twice daily—morning and night—for best results.
Can I use it with Vitamin C, retinol, or acids?
Yes. It layers well with most active ingredients. Apply this serum first after cleansing, then follow with other treatments.
Why do I feel a slight tingling after applying it?
Some users may experience a mild, temporary sensation due to active ingredients interacting with the skin. This typically fades quickly and is not a cause for concern.
How long should I use it before judging results?
You should use it consistently for at least 6–8 weeks to properly evaluate improvements in tone, texture, and visible sun damage.
Free Shipping on US Orders $50+
60-Day Money-Back Guarantee
Dermatologist-Approved
Free Shipping on US Orders $50+
60-Day Money-Back Guarantee
Dermatologist-Approved
Free Shipping on US Orders $50+
60-Day Money-Back Guarantee
Dermatologist-Approved
Trusted by 50,000+ Customers & Physicians
READY TO REPAIR YOUR SKIN
AT THE SOURCE?
Join thousands using DNA Youth Recovery daily to target visible
signs of aging at the source.
START YOUR REPAIR JOURNEY ➝
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